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Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature

Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory disease of the breast, the etiology of which, has still not been elucidated. There have been several mechanisms proposed to explain the pathogenesis. Since the first description of the disease, it has proved itself to be a great diagn...

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Detalles Bibliográficos
Autores principales: Mathew Thomas, Vinay, Alexander, Swetha Ann, Bindal, Poorva, Vredenburgh, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059874/
https://www.ncbi.nlm.nih.gov/pubmed/32195062
http://dx.doi.org/10.7759/cureus.6895
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author Mathew Thomas, Vinay
Alexander, Swetha Ann
Bindal, Poorva
Vredenburgh, James
author_facet Mathew Thomas, Vinay
Alexander, Swetha Ann
Bindal, Poorva
Vredenburgh, James
author_sort Mathew Thomas, Vinay
collection PubMed
description Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory disease of the breast, the etiology of which, has still not been elucidated. There have been several mechanisms proposed to explain the pathogenesis. Since the first description of the disease, it has proved itself to be a great diagnostic and therapeutic challenge. It is very often misdiagnosed as cancer, resulting in myriad workup by the physician and great distress to the patient. Clear guidelines as to the management have still not been described. Here, we describe two patients who presented with IGM and have been successfully treated. The first patient was treated with a combination of steroids and antibiotics. The second patient achieved remission of the disease with antibiotics alone. We also propose an algorithm for the management of IGM.
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spelling pubmed-70598742020-03-19 Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature Mathew Thomas, Vinay Alexander, Swetha Ann Bindal, Poorva Vredenburgh, James Cureus Pathology Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory disease of the breast, the etiology of which, has still not been elucidated. There have been several mechanisms proposed to explain the pathogenesis. Since the first description of the disease, it has proved itself to be a great diagnostic and therapeutic challenge. It is very often misdiagnosed as cancer, resulting in myriad workup by the physician and great distress to the patient. Clear guidelines as to the management have still not been described. Here, we describe two patients who presented with IGM and have been successfully treated. The first patient was treated with a combination of steroids and antibiotics. The second patient achieved remission of the disease with antibiotics alone. We also propose an algorithm for the management of IGM. Cureus 2020-02-05 /pmc/articles/PMC7059874/ /pubmed/32195062 http://dx.doi.org/10.7759/cureus.6895 Text en Copyright © 2020, Mathew Thomas et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Mathew Thomas, Vinay
Alexander, Swetha Ann
Bindal, Poorva
Vredenburgh, James
Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature
title Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature
title_full Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature
title_fullStr Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature
title_full_unstemmed Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature
title_short Idiopathic Granulomatous Mastitis-A Mystery Yet to be Unraveled: A Case Series and Review of Literature
title_sort idiopathic granulomatous mastitis-a mystery yet to be unraveled: a case series and review of literature
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059874/
https://www.ncbi.nlm.nih.gov/pubmed/32195062
http://dx.doi.org/10.7759/cureus.6895
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