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Advanced paternal age directly impacts mouse embryonic placental imprinting

The placental epigenome plays a critical role in regulating mammalian growth and development. Alterations to placental methylation, often observed at imprinted genes, can lead to adverse pregnancy complications such as intrauterine growth restriction and preterm birth. Similar associations have been...

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Detalles Bibliográficos
Autores principales: Denomme, Michelle M., Parks, Jason C., McCallie, Blair R., McCubbin, Nathan I., Schoolcraft, William B., Katz-Jaffe, Mandy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059926/
https://www.ncbi.nlm.nih.gov/pubmed/32142542
http://dx.doi.org/10.1371/journal.pone.0229904