Cargando…

Childhood asthma in the new omics era: challenges and perspectives

PURPOSE OF REVIEW: Childhood asthma is a heterogeneous inflammatory disease comprising different phenotypes and endotypes and, particularly in its severe forms, has a large impact on the quality-of-life of patients and caregivers. The application of advanced omics technologies provides useful insigh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Golebski, Korneliusz, Kabesch, Michael, Melén, Erik, Potočnik, Uroš, van Drunen, Cornelis M., Reinarts, Susanne, Maitland-van der Zee, Anke H., Vijverberg, Susanne J.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	PEDIATRIC ASTHMA AND DEVELOPMENT OF ATOPY: Edited by Andy Liu and Pasquale Comberiati
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060050/ https://www.ncbi.nlm.nih.gov/pubmed/31985545 http://dx.doi.org/10.1097/ACI.0000000000000626

Ejemplares similares

Predicting the course of asthma from childhood until early adulthood
por: Koefoed, Hans Jacob L., et al.
Publicado: (2022)

Precision medicine in severe pediatric asthma: opportunities and challenges
por: Vijverberg, Susanne J.H., et al.
Publicado: (2020)

Expert meeting report: towards a joint European roadmap to address the unmet needs and priorities of paediatric asthma patients on biologic therapy
por: Golebski, Korneliusz, et al.
Publicado: (2021)

Developments in the Management of Severe Asthma in Children and Adolescents: Focus on Dupilumab and Tezepelumab
por: van Dijk, Yoni E., et al.
Publicado: (2023)

Effectiveness, usability and acceptability of a smart inhaler programme in patients with asthma: protocol of the multicentre, pragmatic, open-label, cluster randomised controlled ACCEPTANCE trial
por: van de Hei, Susanne J, et al.
Publicado: (2022)

Association between tobacco product use and asthma among US adults from the Population Assessment of Tobacco and Health (PATH) Study waves 2–4
por: Brunette, Mary F, et al.
Publicado: (2023)

A System Pharmacology Multi-Omics Approach toward Uncontrolled Pediatric Asthma
por: Abdel-Aziz, Mahmoud I., et al.
Publicado: (2021)

One time a day mometasone/indacaterol fixed-dose combination versus two times a day fluticasone/salmeterol in patients with inadequately controlled asthma: pooled analysis from PALLADIUM and IRIDIUM studies
por: Chapman, Kenneth, et al.
Publicado: (2021)

Characteristics of new adult users of mepolizumab with asthma in the USA
por: Wu, Ann Chen, et al.
Publicado: (2021)

Phenotypic characteristics and asthma severity in an East African cohort of adults and adolescents with asthma: findings from the African severe asthma project
por: Kirenga, Bruce, et al.
Publicado: (2020)

Phenotyping asthma with airflow obstruction in middle-aged and older adults: a CADSET clinical research collaboration
por: Bertels, Xander, et al.
Publicado: (2023)

uPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium
por: Stewart, Ceri E, et al.
Publicado: (2011)

Risk factors for atopic and non-atopic asthma in a rural area of Ecuador
por: Moncayo, Ana Lucia, et al.
Publicado: (2010)

Refractory asthma in the UK: cross-sectional findings from a UK multicentre registry
por: Heaney, Liam G, et al.
Publicado: (2010)

Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes
por: Gupta, Sumit, et al.
Publicado: (2010)

Adverse effects of salmeterol in asthma: a neuronal perspective
por: Lommatzsch, M, et al.
Publicado: (2009)

Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the β(2) agonist vilanterol administered once daily for 52 weeks in patients ≥12 years old with asthma: a randomised trial
por: Busse, William W, et al.
Publicado: (2013)

Combination of budesonide/formoterol on demand improves asthma control by reducing exercise-induced bronchoconstriction
por: Lazarinis, Nikolaos, et al.
Publicado: (2014)

Once-daily fluticasone furoate (FF)/vilanterol reduces risk of severe exacerbations in asthma versus FF alone
por: Bateman, Eric D, et al.
Publicado: (2014)

Tolerability in man following inhalation dosing of the selective TLR7 agonist, AZD8848
por: Delaney, Stephen, et al.
Publicado: (2016)

Three-month validation of a turbuhaler electronic monitoring device: implications for asthma clinical trial use
por: Pilcher, Janine, et al.
Publicado: (2015)

Economic analysis of temperature-controlled laminar airflow (TLA) for the treatment of patients with severe persistent allergic asthma
por: Brazier, Peter, et al.
Publicado: (2016)

Effects of body mass index, tobacco smoking, alcohol drinking and solid fuel use on the risk of asthma: Individual Participant Data (IPD) meta-analysis of 175 000 individuals from 51 nationally representative surveys
por: Patra, Jayadeep, et al.
Publicado: (2016)

Factors associated with relapse in adult patients discharged from the emergency department following acute asthma: a systematic review
por: Hill, Jesse, et al.
Publicado: (2017)

Step 4: stick or twist? A review of asthma therapy
por: Slater, Mariel G, et al.
Publicado: (2016)

What are the pros and cons of electronically monitoring inhaler use in asthma? A multistakeholder perspective
por: Howard, Sam, et al.
Publicado: (2016)

Differentiation of quantitative CT imaging phenotypes in asthma versus COPD
por: Choi, Sanghun, et al.
Publicado: (2017)

Sputum colour can identify patients with neutrophilic inflammation in asthma
por: Pabreja, Kavita, et al.
Publicado: (2017)

Healthcare resource use and costs of severe, uncontrolled eosinophilic asthma in the UK general population
por: Kerkhof, Marjan, et al.
Publicado: (2018)

At-risk children with asthma (ARC): a systematic review
por: Buelo, Audrey, et al.
Publicado: (2018)

Concordance of opinions between patients and physicians and their relationship with symptomatic control and future risk in patients with moderate–severe asthma
por: Crespo-Lessmann, Astrid, et al.
Publicado: (2017)

Description of the protocol for the PRACTICAL study: a randomised controlled trial of the efficacy and safety of ICS/LABA reliever therapy in asthma
por: Fingleton, James, et al.
Publicado: (2017)

Assessing the use of BreatheSmart® mobile technology in adult patients with asthma: a remote observational study
por: Melvin, Emilie, et al.
Publicado: (2017)

Chlamydia pneumoniae-induced tumour necrosis factor alpha responses are lower in children with asthma compared with non-asthma
por: Smith-Norowitz, Tamar Anne, et al.
Publicado: (2018)

Sex and intimacy in people with severe asthma: a qualitative study
por: Holmes, Leanne Jo, et al.
Publicado: (2019)

Gut microbiota relationships to lung function and adult asthma phenotype: a pilot study
por: Begley, Lesa, et al.
Publicado: (2018)

Genetic and observational evidence supports a causal role of sex hormones on the development of asthma
por: Arathimos, Ryan, et al.
Publicado: (2019)

Persistent variations in national asthma mortality, hospital admissions and prevalence by socioeconomic status and region in England
por: Gupta, Ramyani P, et al.
Publicado: (2018)

Novel pharmacist-led intervention secures the minimally important difference (MID) in Asthma Control Test (ACT) score: better outcomes for patients and the healthcare provider
por: Tinelli, Michela, et al.
Publicado: (2018)

Rural to urban migration is associated with increased prevalence of childhood wheeze in a Latin-American city
por: Rodriguez, Alejandro, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ir7jpmtbg99v198ktu0da7mfb2