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Lymph Node Positivity in One-Step Nucleic Acid Amplification is a Prognostic Factor for Postoperative Cancer Recurrence in Patients with Stage II Colorectal Cancer: A Prospective, Multicenter Study
BACKGROUND: For colorectal cancer (CRC) patients, the standard histological lymph node (LN) evaluation has low sensitivity. Our previously developed one-step nucleic acid amplification (OSNA™) assay measures cytokeratin 19 gene expression in whole LNs. We recently showed that 17.6% of pN0 stage II C...
Autores principales: | Itabashi, Michio, Yamamoto, Hirofumi, Tomita, Naohiro, Inomata, Masafumi, Murata, Kohei, Hayashi, Shigeoki, Miyake, Yasuhiro, Igarashi, Seiji, Kato, Takeshi, Noura, Shingo, Furuhata, Tomohisa, Ozawa, Heita, Takemasa, Ichiro, Yasui, Masayoshi, Takeyama, Hiroshi, Okamura, Shu, Ohno, Yuko, Matsuura, Nariaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060165/ https://www.ncbi.nlm.nih.gov/pubmed/31722072 http://dx.doi.org/10.1245/s10434-019-07971-y |
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