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Loxoprofen‐induced bullous fixed drug eruption

A 49‐year‐old housewife with a long‐standing migraine presented with "spells" of intensely itchy, well‐circumscribed, erythematous patches over the flexor aspect of her left wrist and palm repeatedly for the last 15 years. Detailed history revealed her oral loxoprofen use for migraine head...

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Detalles Bibliográficos
Autores principales: Yamada, Takayuki, Sakemi, Hideta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060290/
https://www.ncbi.nlm.nih.gov/pubmed/32161698
http://dx.doi.org/10.1002/jgf2.288
Descripción
Sumario:A 49‐year‐old housewife with a long‐standing migraine presented with "spells" of intensely itchy, well‐circumscribed, erythematous patches over the flexor aspect of her left wrist and palm repeatedly for the last 15 years. Detailed history revealed her oral loxoprofen use for migraine headaches preceding rash development. Although a patch test was negative, inadvertent ingestion of the drug by the patient reproduced the rash within a few hours, thereby establishing the diagnosis of loxoprofen‐induced bullous fixed drug eruption.[Image: see text]