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Phosphatidylinositol 3‐kinase‐δ controls endoplasmic reticulum membrane fluidity and permeability in fungus‐induced allergic inflammation in mice

BACKGROUND AND PURPOSE: Phosphatidylinositol 3‐kinase (PI3K), especially PI3K‐δ, and endoplasmic reticulum (ER) stress play important roles in refractory asthma induced by the fungus Aspergillus fumigatus through mechanisms that are not well understood. Here we have investigated these mechanisms, us...

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Detalles Bibliográficos
Autores principales: Lee, Hwa‐Young, Lee, Geum‐Hwa, Kim, Hyung‐Ryong, Lee, Yong‐Chul, Chae, Han‐Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060358/
https://www.ncbi.nlm.nih.gov/pubmed/31713846
http://dx.doi.org/10.1111/bph.14917

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