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Discovery of chemical probes that suppress Wnt/β‐catenin signaling through high‐throughput screening

Aberrant activation of the Wnt/β‐catenin signaling pathway has been observed in a wide range of human tumors. Deregulation of the pathway is closely linked to various aspects of human carcinogenesis such as cell viability, regulation of cell cycle, epithelial‐mesenchymal transition, and maintenance...

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Detalles Bibliográficos
Autores principales:	Yamaguchi, Kiyoshi, Nagatoishi, Satoru, Tsumoto, Kouhei, Furukawa, Yoichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060471/ https://www.ncbi.nlm.nih.gov/pubmed/31912579 http://dx.doi.org/10.1111/cas.14297

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