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Kinesin-5 Eg5 is essential for spindle assembly and chromosome alignment of mouse spermatocytes

BACKGROUND: Microtubule organization is essential for bipolar spindle assembly and chromosome segregation, which contribute to genome stability. Kinesin-5 Eg5 is known to be a crucial regulator in centrosome separation and spindle assembly in mammalian somatic cells, however, the functions and mecha...

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Detalles Bibliográficos
Autores principales: She, Zhen-Yu, Zhong, Ning, Yu, Kai-Wei, Xiao, Yu, Wei, Ya-Lan, Lin, Yang, Li, Yue-Ling, Lu, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060529/
https://www.ncbi.nlm.nih.gov/pubmed/32165913
http://dx.doi.org/10.1186/s13008-020-00063-4