Cargando…
Kinesin-5 Eg5 is essential for spindle assembly and chromosome alignment of mouse spermatocytes
BACKGROUND: Microtubule organization is essential for bipolar spindle assembly and chromosome segregation, which contribute to genome stability. Kinesin-5 Eg5 is known to be a crucial regulator in centrosome separation and spindle assembly in mammalian somatic cells, however, the functions and mecha...
Autores principales: | She, Zhen-Yu, Zhong, Ning, Yu, Kai-Wei, Xiao, Yu, Wei, Ya-Lan, Lin, Yang, Li, Yue-Ling, Lu, Ming-Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060529/ https://www.ncbi.nlm.nih.gov/pubmed/32165913 http://dx.doi.org/10.1186/s13008-020-00063-4 |
Ejemplares similares
-
Kinesin-5 Eg5 is essential for spindle assembly, chromosome stability and organogenesis in development
por: Yu, Wen-Xin, et al.
Publicado: (2022) -
Lamin B Counteracts the Kinesin Eg5 to Restrain Spindle Pole Separation during Spindle Assembly
por: Goodman, Benjamin, et al.
Publicado: (2010) -
Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5
por: Kapoor, Tarun M., et al.
Publicado: (2000) -
Kinesin-7 CENP-E regulates chromosome alignment and genome stability of spermatogenic cells
por: She, Zhen-Yu, et al.
Publicado: (2020) -
The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles
por: Miyamoto, David T., et al.
Publicado: (2004)