MiR-7 reduces the BCSC subset by inhibiting XIST to modulate the miR-92b/Slug/ESA axis and inhibit tumor growth

BACKGROUND: Breast cancer stem cells (BCSCs) are typically seed cells of breast tumor that initiate and maintain tumor growth. MiR-7, as a cancer inhibitor, decreases the BCSC subset and inhibits tumor progression through mechanisms that remain unknown. METHODS: We examined miR-7 expression in breas...

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Detalles Bibliográficos
Autores principales: Li, Miao, Pan, Meng, You, Chengzhong, Zhao, Fengshu, Wu, Di, Guo, Mei, Xu, Hui, Shi, Fangfang, Zheng, Danfeng, Dou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060548/
https://www.ncbi.nlm.nih.gov/pubmed/32143670
http://dx.doi.org/10.1186/s13058-020-01264-z

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