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Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain
BACKGROUND: Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the epigenomic alterations and transcription factors (TFs) which underlie these...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060551/ https://www.ncbi.nlm.nih.gov/pubmed/32143622 http://dx.doi.org/10.1186/s12920-020-0695-0 |