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Intranasally administered protein coated chitosan nanoparticles encapsulating influenza H9N2 HA2 and M2e mRNA molecules elicit protective immunity against avian influenza viruses in chickens

Chitosan nanoparticles (CNPs) represent an efficient vaccination tool to deliver immunogenic antigens to the antigen-presenting cells (APCs), which subsequently stimulate protective immune responses against infectious diseases. Herein, we prepared CNPs encapsulating mRNA molecules followed by surfac...

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Detalles Bibliográficos
Autores principales:	Hajam, Irshad Ahmed, Senevirathne, Amal, Hewawaduge, Chamit, Kim, Jehyoung, Lee, John Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060564/ https://www.ncbi.nlm.nih.gov/pubmed/32143695 http://dx.doi.org/10.1186/s13567-020-00762-4

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