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Disseminated melioidosis in early pregnancy - an unproven cause of foetal loss

BACKGROUND: Melioidosis is a potentially life-threatening infection caused by the Gram-negative bacterium Burkholderia pseudomallei. Melioidosis is difficult to diagnose due to its diverse clinical manifestations, which often delays administration of appropriate antibiotic therapy. CASE PRESENTATION...

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Autores principales: Chang, Chee Yik, Lau, Nina Lee Jing, Currie, Bart J., Podin, Yuwana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060584/
https://www.ncbi.nlm.nih.gov/pubmed/32143598
http://dx.doi.org/10.1186/s12879-020-4937-8
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author Chang, Chee Yik
Lau, Nina Lee Jing
Currie, Bart J.
Podin, Yuwana
author_facet Chang, Chee Yik
Lau, Nina Lee Jing
Currie, Bart J.
Podin, Yuwana
author_sort Chang, Chee Yik
collection PubMed
description BACKGROUND: Melioidosis is a potentially life-threatening infection caused by the Gram-negative bacterium Burkholderia pseudomallei. Melioidosis is difficult to diagnose due to its diverse clinical manifestations, which often delays administration of appropriate antibiotic therapy. CASE PRESENTATION: Melioidosis is uncommon in pregnancy but both spontaneous abortion and neonatal melioidosis have been reported. We report a case of bacteraemic melioidosis in a young woman with a subsequent spontaneous abortion, with B. pseudomallei cultured from a high vaginal swab as well as blood. CONCLUSION: It remains unclear in this and previously reported cases as to whether the maternal melioidosis was sexually transmitted.
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spelling pubmed-70605842020-03-12 Disseminated melioidosis in early pregnancy - an unproven cause of foetal loss Chang, Chee Yik Lau, Nina Lee Jing Currie, Bart J. Podin, Yuwana BMC Infect Dis Case Report BACKGROUND: Melioidosis is a potentially life-threatening infection caused by the Gram-negative bacterium Burkholderia pseudomallei. Melioidosis is difficult to diagnose due to its diverse clinical manifestations, which often delays administration of appropriate antibiotic therapy. CASE PRESENTATION: Melioidosis is uncommon in pregnancy but both spontaneous abortion and neonatal melioidosis have been reported. We report a case of bacteraemic melioidosis in a young woman with a subsequent spontaneous abortion, with B. pseudomallei cultured from a high vaginal swab as well as blood. CONCLUSION: It remains unclear in this and previously reported cases as to whether the maternal melioidosis was sexually transmitted. BioMed Central 2020-03-06 /pmc/articles/PMC7060584/ /pubmed/32143598 http://dx.doi.org/10.1186/s12879-020-4937-8 Text en © The Author(s). 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Chang, Chee Yik
Lau, Nina Lee Jing
Currie, Bart J.
Podin, Yuwana
Disseminated melioidosis in early pregnancy - an unproven cause of foetal loss
title Disseminated melioidosis in early pregnancy - an unproven cause of foetal loss
title_full Disseminated melioidosis in early pregnancy - an unproven cause of foetal loss
title_fullStr Disseminated melioidosis in early pregnancy - an unproven cause of foetal loss
title_full_unstemmed Disseminated melioidosis in early pregnancy - an unproven cause of foetal loss
title_short Disseminated melioidosis in early pregnancy - an unproven cause of foetal loss
title_sort disseminated melioidosis in early pregnancy - an unproven cause of foetal loss
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060584/
https://www.ncbi.nlm.nih.gov/pubmed/32143598
http://dx.doi.org/10.1186/s12879-020-4937-8
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