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Initiation and propagation of α-synuclein aggregation in the nervous system

The two main pathological hallmarks of Parkinson’s disease are loss of dopamine neurons in the substantia nigra pars compacta and proteinaceous amyloid fibrils composed mostly of α-synuclein, called Lewy pathology. Levodopa to enhance dopaminergic transmission remains one of the most effective treat...

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Detalles Bibliográficos
Autores principales:	Hijaz, Baraa A., Volpicelli-Daley, Laura A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060612/ https://www.ncbi.nlm.nih.gov/pubmed/32143659 http://dx.doi.org/10.1186/s13024-020-00368-6

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