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Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex
BACKGROUND: A comprehensive understanding of the pre-existing genetic variation in genes associated with antibiotic resistance in the Mycobacterium tuberculosis complex (MTBC) is needed to accurately interpret whole-genome sequencing data for genotypic drug susceptibility testing (DST). METHODS: We...
Autores principales: | Merker, Matthias, Kohl, Thomas A., Barilar, Ivan, Andres, Sönke, Fowler, Philip W., Chryssanthou, Erja, Ängeby, Kristian, Jureen, Pontus, Moradigaravand, Danesh, Parkhill, Julian, Peacock, Sharon J., Schön, Thomas, Maurer, Florian P., Walker, Timothy, Köser, Claudio, Niemann, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060619/ https://www.ncbi.nlm.nih.gov/pubmed/32143680 http://dx.doi.org/10.1186/s13073-020-00726-5 |
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