Cargando…

Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex

BACKGROUND: A comprehensive understanding of the pre-existing genetic variation in genes associated with antibiotic resistance in the Mycobacterium tuberculosis complex (MTBC) is needed to accurately interpret whole-genome sequencing data for genotypic drug susceptibility testing (DST). METHODS: We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Merker, Matthias, Kohl, Thomas A., Barilar, Ivan, Andres, Sönke, Fowler, Philip W., Chryssanthou, Erja, Ängeby, Kristian, Jureen, Pontus, Moradigaravand, Danesh, Parkhill, Julian, Peacock, Sharon J., Schön, Thomas, Maurer, Florian P., Walker, Timothy, Köser, Claudio, Niemann, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060619/ https://www.ncbi.nlm.nih.gov/pubmed/32143680 http://dx.doi.org/10.1186/s13073-020-00726-5

Ejemplares similares

What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis
por: Heyckendorf, Jan, et al.
Publicado: (2018)

Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin
por: Yu, Xia, et al.
Publicado: (2016)

Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance
por: Nakatani, Yoshio, et al.
Publicado: (2017)

Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain GenoType MTBDRsl Assays
por: Ajileye, Adebisi, et al.
Publicado: (2017)

Evolution and Epidemiology of Multidrug-Resistant Klebsiella pneumoniae in the United Kingdom and Ireland
por: Moradigaravand, Danesh, et al.
Publicado: (2017)

Population Structure of Multidrug-Resistant Klebsiella oxytoca within Hospitals across the United Kingdom and Ireland Identifies Sharing of Virulence and Resistance Genes with K. pneumoniae
por: Moradigaravand, Danesh, et al.
Publicado: (2017)

dfrA thyA Double Deletion in para-Aminosalicylic Acid-Resistant Mycobacterium tuberculosis Beijing Strains
por: Moradigaravand, Danesh, et al.
Publicado: (2016)

No Evidence for Acquired Mutations Associated with Cytochrome bc(1) Inhibitor Resistance in 13,559 Clinical Mycobacterium tuberculosis Complex Isolates
por: Rybniker, Jan, et al.
Publicado: (2018)

Whole-genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates from Myanmar
por: Aung, Htin Lin, et al.
Publicado: (2016)

Recent independent emergence of multiple multidrug-resistant Serratia marcescens clones within the United Kingdom and Ireland
por: Moradigaravand, Danesh, et al.
Publicado: (2016)

Transmission Dynamics of a Mycobacterium tuberculosis Complex Outbreak in an Indigenous Population in the Colombian Amazon Region
por: Pérez-Llanos, Francy J., et al.
Publicado: (2023)

Delineating Mycobacterium abscessus population structure and transmission employing high-resolution core genome multilocus sequence typing
por: Diricks, Margo, et al.
Publicado: (2022)

In vitro activity of new combinations of β-lactam and β-lactamase inhibitors against the Mycobacterium tuberculosis complex
por: Economou Lundeberg, Elin, et al.
Publicado: (2023)

Comment on: Characterization of the embB gene in Mycobacterium tuberculosis isolates from Barcelona and rapid detection of main mutations related to ethambutol resistance using a low-density DNA array
por: Köser, Claudio U., et al.
Publicado: (2014)

The in vitro effect of new combinations of carbapenem–β-lactamase inhibitors for Mycobacterium abscessus
por: Fröberg, Gabrielle, et al.
Publicado: (2023)

Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak
por: Godfroid, Maxime, et al.
Publicado: (2020)

A Rough Colony Morphology of Mycobacterium abscessus Is Associated With Cavitary Pulmonary Disease and Poor Clinical Outcome
por: Hedin, Wilhelm, et al.
Publicado: (2023)

Genetic diversity within Mycobacterium tuberculosis complex impacts on the accuracy of genotypic pyrazinamide drug-susceptibility assay
por: Köser, Claudio U., et al.
Publicado: (2014)

Microevolution of Mycobacterium tuberculosis Subpopulations and Heteroresistance in a Patient Receiving 27 Years of Tuberculosis Treatment in Germany
por: Sonnenkalb, Lindsay, et al.
Publicado: (2021)

Detection of low-frequency resistance-mediating SNPs in next-generation sequencing data of Mycobacterium tuberculosis complex strains with binoSNP
por: Dreyer, Viola, et al.
Publicado: (2020)

Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Beijing Clades, Ukraine, 2015
por: Merker, Matthias, et al.
Publicado: (2020)

Whole genome sequencing reveals high-resolution epidemiological links between clinical and environmental Klebsiella pneumoniae
por: Runcharoen, Chakkaphan, et al.
Publicado: (2017)

Emergence of bedaquiline resistance in a high tuberculosis burden country
por: Chesov, Elena, et al.
Publicado: (2022)

Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia
por: Tessema, Belay, et al.
Publicado: (2013)

Drug-resistance profiling and transmission dynamics of multidrug-resistant Mycobacterium tuberculosis in Saudi Arabia revealed by whole genome sequencing
por: Al-Ghafli, Hawra, et al.
Publicado: (2018)

Within-host evolution of Enterococcus faecium during longitudinal carriage and transition to bloodstream infection in immunocompromised patients
por: Moradigaravand, Danesh, et al.
Publicado: (2017)

Rapid microarray-based assay for detection of pyrazinamide resistant Mycobacterium tuberculosis
por: Havlicek, Juliane, et al.
Publicado: (2019)

MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era
por: Beckert, Patrick, et al.
Publicado: (2020)

Ancient and recent differences in the intrinsic susceptibility of Mycobacterium tuberculosis complex to pretomanid
por: Bateson, Anna, et al.
Publicado: (2022)

Resistance to First-Line Anti-TB Drugs Is Associated with Reduced Nitric Oxide Susceptibility in Mycobacterium tuberculosis
por: Idh, Jonna, et al.
Publicado: (2012)

Secretome characterization of clinical isolates from the Mycobacterium abscessus complex provides insight into antigenic differences
por: Cornejo-Granados, Fernanda, et al.
Publicado: (2021)

Investigating resistance in clinical Mycobacterium tuberculosis complex isolates with genomic and phenotypic antimicrobial susceptibility testing: a multicentre observational study
por: Finci, Iris, et al.
Publicado: (2022)

Rapid Microarray-Based Detection of Rifampin, Isoniazid, and Fluoroquinolone Resistance in Mycobacterium tuberculosis by Use of a Single Cartridge
por: Havlicek, Juliane, et al.
Publicado: (2018)

Invasive fungal infection by Peziza ostracoderma in an immunocompromised patient
por: Kinch, Amelie, et al.
Publicado: (2022)

A 24-well plate assay for simultaneous testing of first and second line drugs against Mycobacterium tuberculosis in a high endemic setting
por: Wedajo, Wassihun, et al.
Publicado: (2014)

Transmission patterns of rifampicin resistant Mycobacterium tuberculosis complex strains in Cameroon: a genomic epidemiological study
por: Merker, Matthias, et al.
Publicado: (2021)

High fluoroquinolone resistance proportions among multidrug-resistant tuberculosis driven by dominant L2 Mycobacterium tuberculosis clones in the Mumbai Metropolitan Region
por: Dreyer, Viola, et al.
Publicado: (2022)

The impact of natural transformation on adaptation in spatially structured bacterial populations
por: Moradigaravand, Danesh, et al.
Publicado: (2014)

The Effect of Bacterial Recombination on Adaptation on Fitness Landscapes with Limited Peak Accessibility
por: Moradigaravand, Danesh, et al.
Publicado: (2012)

Detection of vancomycin-resistant Enterococcus faecium hospital-adapted lineages in municipal wastewater treatment plants indicates widespread distribution and release into the environment
por: Gouliouris, Theodore, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2b5fan7jkt2bm9es4dlnd8g1jm