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On the evolution of protein–adenine binding
Proteins’ interactions with ancient ligands may reveal how molecular recognition emerged and evolved. We explore how proteins recognize adenine: a planar rigid fragment found in the most common and ancient ligands. We have developed a computational pipeline that extracts protein–adenine complexes fr...
Autores principales: | Narunsky, Aya, Kessel, Amit, Solan, Ron, Alva, Vikram, Kolodny, Rachel, Ben-Tal, Nir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060716/ https://www.ncbi.nlm.nih.gov/pubmed/32079721 http://dx.doi.org/10.1073/pnas.1911349117 |
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