Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium

In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally...

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Detalles Bibliográficos
Autores principales: Zlatskiy, I. A., Zlatska, A. V., Antipova, N. V., Dolenko, S. A., Gordiienko, I. M., Gubar, O. S., Vasyliev, R. G., Zubov, D. A., Novikova, S. N., Syroeshkin, A. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060866/
https://www.ncbi.nlm.nih.gov/pubmed/32158363
http://dx.doi.org/10.1155/2020/2373021
Descripción
Sumario:In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally sensitive to the D/H ratios in the culture medium (system) as well as to the different cell types (cancer vs normal cells).

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