Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium

In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally...

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Autores principales: Zlatskiy, I. A., Zlatska, A. V., Antipova, N. V., Dolenko, S. A., Gordiienko, I. M., Gubar, O. S., Vasyliev, R. G., Zubov, D. A., Novikova, S. N., Syroeshkin, A. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060866/
https://www.ncbi.nlm.nih.gov/pubmed/32158363
http://dx.doi.org/10.1155/2020/2373021
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author Zlatskiy, I. A.
Zlatska, A. V.
Antipova, N. V.
Dolenko, S. A.
Gordiienko, I. M.
Gubar, O. S.
Vasyliev, R. G.
Zubov, D. A.
Novikova, S. N.
Syroeshkin, A. V.
author_facet Zlatskiy, I. A.
Zlatska, A. V.
Antipova, N. V.
Dolenko, S. A.
Gordiienko, I. M.
Gubar, O. S.
Vasyliev, R. G.
Zubov, D. A.
Novikova, S. N.
Syroeshkin, A. V.
author_sort Zlatskiy, I. A.
collection PubMed
description In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally sensitive to the D/H ratios in the culture medium (system) as well as to the different cell types (cancer vs normal cells).
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spelling pubmed-70608662020-03-10 Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium Zlatskiy, I. A. Zlatska, A. V. Antipova, N. V. Dolenko, S. A. Gordiienko, I. M. Gubar, O. S. Vasyliev, R. G. Zubov, D. A. Novikova, S. N. Syroeshkin, A. V. ScientificWorldJournal Research Article In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally sensitive to the D/H ratios in the culture medium (system) as well as to the different cell types (cancer vs normal cells). Hindawi 2020-02-25 /pmc/articles/PMC7060866/ /pubmed/32158363 http://dx.doi.org/10.1155/2020/2373021 Text en Copyright © 2020 I. A. Zlatskiy et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zlatskiy, I. A.
Zlatska, A. V.
Antipova, N. V.
Dolenko, S. A.
Gordiienko, I. M.
Gubar, O. S.
Vasyliev, R. G.
Zubov, D. A.
Novikova, S. N.
Syroeshkin, A. V.
Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium
title Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium
title_full Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium
title_fullStr Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium
title_full_unstemmed Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium
title_short Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium
title_sort comparative analysis of the different dyes' potential to assess human normal and cancer cell viability in vitro under different d/h ratios in a culture medium
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060866/
https://www.ncbi.nlm.nih.gov/pubmed/32158363
http://dx.doi.org/10.1155/2020/2373021
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