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Troubles lipidiques et glucidiques à risque cardio-vasculaires chez les personnes vivant avec le virus d’immunodéficience humaine sous traitement antirétroviral: cas du centre de prise en charge médicale de l’ONG Espoir-Vie-Togo à Lomé

Antiretroviral drugs are responsible for side effects or undesirable effects. These may include redistribution of adipose tissue and disorders of the lipid or carbohydrate metabolism. Given the growing number of people living with HIV (PLHIV) on antiretroviral therapy, it is necessary to assess the...

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Autores principales: Agbeko, Djagadou Kodjo, Toyi, Tchamdja, Lihanimpo, Djalogue, Dzidzonu, Némi Komi, Laconi, Kaaga, Abago, Balaka, Awalou, Djibril Mohaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060946/
https://www.ncbi.nlm.nih.gov/pubmed/32180877
http://dx.doi.org/10.11604/pamj.2019.34.203.20600
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author Agbeko, Djagadou Kodjo
Toyi, Tchamdja
Lihanimpo, Djalogue
Dzidzonu, Némi Komi
Laconi, Kaaga
Abago, Balaka
Awalou, Djibril Mohaman
author_facet Agbeko, Djagadou Kodjo
Toyi, Tchamdja
Lihanimpo, Djalogue
Dzidzonu, Némi Komi
Laconi, Kaaga
Abago, Balaka
Awalou, Djibril Mohaman
author_sort Agbeko, Djagadou Kodjo
collection PubMed
description Antiretroviral drugs are responsible for side effects or undesirable effects. These may include redistribution of adipose tissue and disorders of the lipid or carbohydrate metabolism. Given the growing number of people living with HIV (PLHIV) on antiretroviral therapy, it is necessary to assess the frequency of disorders of carbohydrate and lipid metabolism in patients who are on antiretroviral therapy (ARV). Our analysis focused on 493 patients with HIV/AIDS and on ARV treated in the Medical Centre of the ONG Espoir Vie Togo, Lomé. Paraclinical data such as blood glucose, serum total cholesterol, triglycerides, HDL cholesterol and LDL cholesterol were studied. The study showed the following anomalies: hypercholesterolemia, LDL hypercholesterolemia, HDL-hypocholesterolemia were found in 41.4%, 23.5% and 17.4% of patients respectively. The incidence of hyperglycemia was 12.4%. It is important to note that the incidence of lipido carbohydrate disorders was higher in patients receiving treatment schedule including protease inhibitors. The study also highlighted that 31.2% of patients with disorders of carbohydrate and lipid metabolism were overweight or obese. The incidence of these disorders differs depending on whether patients were under triple therapy including protease inhibitors or not.
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spelling pubmed-70609462020-03-16 Troubles lipidiques et glucidiques à risque cardio-vasculaires chez les personnes vivant avec le virus d’immunodéficience humaine sous traitement antirétroviral: cas du centre de prise en charge médicale de l’ONG Espoir-Vie-Togo à Lomé Agbeko, Djagadou Kodjo Toyi, Tchamdja Lihanimpo, Djalogue Dzidzonu, Némi Komi Laconi, Kaaga Abago, Balaka Awalou, Djibril Mohaman Pan Afr Med J Case Series Antiretroviral drugs are responsible for side effects or undesirable effects. These may include redistribution of adipose tissue and disorders of the lipid or carbohydrate metabolism. Given the growing number of people living with HIV (PLHIV) on antiretroviral therapy, it is necessary to assess the frequency of disorders of carbohydrate and lipid metabolism in patients who are on antiretroviral therapy (ARV). Our analysis focused on 493 patients with HIV/AIDS and on ARV treated in the Medical Centre of the ONG Espoir Vie Togo, Lomé. Paraclinical data such as blood glucose, serum total cholesterol, triglycerides, HDL cholesterol and LDL cholesterol were studied. The study showed the following anomalies: hypercholesterolemia, LDL hypercholesterolemia, HDL-hypocholesterolemia were found in 41.4%, 23.5% and 17.4% of patients respectively. The incidence of hyperglycemia was 12.4%. It is important to note that the incidence of lipido carbohydrate disorders was higher in patients receiving treatment schedule including protease inhibitors. The study also highlighted that 31.2% of patients with disorders of carbohydrate and lipid metabolism were overweight or obese. The incidence of these disorders differs depending on whether patients were under triple therapy including protease inhibitors or not. The African Field Epidemiology Network 2019-12-18 /pmc/articles/PMC7060946/ /pubmed/32180877 http://dx.doi.org/10.11604/pamj.2019.34.203.20600 Text en © Djagadou Kodjo Agbeko et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Agbeko, Djagadou Kodjo
Toyi, Tchamdja
Lihanimpo, Djalogue
Dzidzonu, Némi Komi
Laconi, Kaaga
Abago, Balaka
Awalou, Djibril Mohaman
Troubles lipidiques et glucidiques à risque cardio-vasculaires chez les personnes vivant avec le virus d’immunodéficience humaine sous traitement antirétroviral: cas du centre de prise en charge médicale de l’ONG Espoir-Vie-Togo à Lomé
title Troubles lipidiques et glucidiques à risque cardio-vasculaires chez les personnes vivant avec le virus d’immunodéficience humaine sous traitement antirétroviral: cas du centre de prise en charge médicale de l’ONG Espoir-Vie-Togo à Lomé
title_full Troubles lipidiques et glucidiques à risque cardio-vasculaires chez les personnes vivant avec le virus d’immunodéficience humaine sous traitement antirétroviral: cas du centre de prise en charge médicale de l’ONG Espoir-Vie-Togo à Lomé
title_fullStr Troubles lipidiques et glucidiques à risque cardio-vasculaires chez les personnes vivant avec le virus d’immunodéficience humaine sous traitement antirétroviral: cas du centre de prise en charge médicale de l’ONG Espoir-Vie-Togo à Lomé
title_full_unstemmed Troubles lipidiques et glucidiques à risque cardio-vasculaires chez les personnes vivant avec le virus d’immunodéficience humaine sous traitement antirétroviral: cas du centre de prise en charge médicale de l’ONG Espoir-Vie-Togo à Lomé
title_short Troubles lipidiques et glucidiques à risque cardio-vasculaires chez les personnes vivant avec le virus d’immunodéficience humaine sous traitement antirétroviral: cas du centre de prise en charge médicale de l’ONG Espoir-Vie-Togo à Lomé
title_sort troubles lipidiques et glucidiques à risque cardio-vasculaires chez les personnes vivant avec le virus d’immunodéficience humaine sous traitement antirétroviral: cas du centre de prise en charge médicale de l’ong espoir-vie-togo à lomé
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060946/
https://www.ncbi.nlm.nih.gov/pubmed/32180877
http://dx.doi.org/10.11604/pamj.2019.34.203.20600
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