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Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial Function

Age-related decline in circulating levels of insulin-like growth factor (IGF)-1 is associated with reduced cognitive function, neuronal aging, and neurodegeneration. Decreased mitochondrial function along with increased reactive oxygen species (ROS) and accumulation of damaged macromolecules are hal...

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Detalles Bibliográficos
Autores principales:	Pharaoh, Gavin, Owen, Daniel, Yeganeh, Alexander, Premkumar, Pavithra, Farley, Julie, Bhaskaran, Shylesh, Ashpole, Nicole, Kinter, Michael, Van Remmen, Holly, Logan, Sreemathi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060968/ https://www.ncbi.nlm.nih.gov/pubmed/31732912 http://dx.doi.org/10.1007/s12035-019-01821-4

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