Cargando…

Hyaluronan 35 kDa enhances epithelial barrier function and protects against the development of murine necrotizing enterocolitis

BACKGROUND: Disruption of tight junctions (TJ) predisposes to bacterial translocation, intestinal inflammation, and necrotizing enterocolitis (NEC). Previously studies showed that hyaluronan (HA), a glycosaminoglycan in human milk, maintains intestinal permeability, enhances intestinal immunity, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Gunasekaran, Aarthi, Eckert, Jeffrey, Burge, Kathryn, Zheng, Wei, Yu, Zhongxin, Kessler, Sean, de la Motte, Carol, Chaaban, Hala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061074/
https://www.ncbi.nlm.nih.gov/pubmed/31499514
http://dx.doi.org/10.1038/s41390-019-0563-9