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Hyaluronan 35 kDa enhances epithelial barrier function and protects against the development of murine necrotizing enterocolitis
BACKGROUND: Disruption of tight junctions (TJ) predisposes to bacterial translocation, intestinal inflammation, and necrotizing enterocolitis (NEC). Previously studies showed that hyaluronan (HA), a glycosaminoglycan in human milk, maintains intestinal permeability, enhances intestinal immunity, and...
Autores principales: | Gunasekaran, Aarthi, Eckert, Jeffrey, Burge, Kathryn, Zheng, Wei, Yu, Zhongxin, Kessler, Sean, de la Motte, Carol, Chaaban, Hala |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061074/ https://www.ncbi.nlm.nih.gov/pubmed/31499514 http://dx.doi.org/10.1038/s41390-019-0563-9 |
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