The macrolide drug erythromycin does not protect the hERG channel from inhibition by thioridazine and terfenadine

The macrolide antibiotic erythromycin has been associated with QT interval prolongation and inhibition of the hERG‐encoded channels responsible for the rapid delayed rectifier K(+) current I((Kr)). It has been suggested that low concentrations of erythromycin may have a protective effect against hER...

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Detalles Bibliográficos
Autores principales: El Harchi, Aziza, Butler, Andrew S., Zhang, Yihong, Dempsey, Christopher E., Hancox, Jules C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061092/
https://www.ncbi.nlm.nih.gov/pubmed/32147975
http://dx.doi.org/10.14814/phy2.14385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061092/
https://www.ncbi.nlm.nih.gov/pubmed/32147975
http://dx.doi.org/10.14814/phy2.14385

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