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Phosphorylation of Tau and α-Synuclein Induced Neurodegeneration in MPTP Mouse Model of Parkinson’s Disease
PURPOSE: Parkinson’s disease (PD) is the second most common neurodegenerative disease. The α-Synuclein is a major component of Lewy bodies and Lewy neurites, the pathologic hallmark of PD. It is known that α-Synuclein is phosphorylated (p-α-Synuclein) in PD and tau-hyperphosphorylation (p-Tau) is al...
Autores principales: | Hu, Shanshan, Hu, Meigui, Liu, Jian, Zhang, Bei, Zhang, Zhen, Zhou, Fiona H, Wang, Liping, Dong, Jianghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061418/ https://www.ncbi.nlm.nih.gov/pubmed/32184604 http://dx.doi.org/10.2147/NDT.S235562 |
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