High-throughput analysis of DNA repair in microplates towards identification of inhibitors

Environmental factors can inhibit DNA repair and cause indirect mutagenic actions. Here the author introduces a recent paper on a novel high-throughput system to analyze the various enzymatic activities involved in base excision repair. Such systems will facilitate the identification of compounds th...

Descripción completa

Detalles Bibliográficos
Autor principal: Kamiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061471/
https://www.ncbi.nlm.nih.gov/pubmed/32165992
http://dx.doi.org/10.1186/s41021-020-00153-3
_version_ 1783504394461904896
author Kamiya, Hiroyuki
author_facet Kamiya, Hiroyuki
author_sort Kamiya, Hiroyuki
collection PubMed
description Environmental factors can inhibit DNA repair and cause indirect mutagenic actions. Here the author introduces a recent paper on a novel high-throughput system to analyze the various enzymatic activities involved in base excision repair. Such systems will facilitate the identification of compounds that suppressively affect DNA repair.
format Online
Article
Text
id pubmed-7061471
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-70614712020-03-12 High-throughput analysis of DNA repair in microplates towards identification of inhibitors Kamiya, Hiroyuki Genes Environ Commentary Environmental factors can inhibit DNA repair and cause indirect mutagenic actions. Here the author introduces a recent paper on a novel high-throughput system to analyze the various enzymatic activities involved in base excision repair. Such systems will facilitate the identification of compounds that suppressively affect DNA repair. BioMed Central 2020-03-09 /pmc/articles/PMC7061471/ /pubmed/32165992 http://dx.doi.org/10.1186/s41021-020-00153-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Commentary
Kamiya, Hiroyuki
High-throughput analysis of DNA repair in microplates towards identification of inhibitors
title High-throughput analysis of DNA repair in microplates towards identification of inhibitors
title_full High-throughput analysis of DNA repair in microplates towards identification of inhibitors
title_fullStr High-throughput analysis of DNA repair in microplates towards identification of inhibitors
title_full_unstemmed High-throughput analysis of DNA repair in microplates towards identification of inhibitors
title_short High-throughput analysis of DNA repair in microplates towards identification of inhibitors
title_sort high-throughput analysis of dna repair in microplates towards identification of inhibitors
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061471/
https://www.ncbi.nlm.nih.gov/pubmed/32165992
http://dx.doi.org/10.1186/s41021-020-00153-3
work_keys_str_mv AT kamiyahiroyuki highthroughputanalysisofdnarepairinmicroplatestowardsidentificationofinhibitors

Ejemplares similares