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Poly(1-vinylimidazole) polyplexes as novel therapeutic gene carriers for lung cancer therapy

The present work explores the ability of poly(1-vinylimidazole) (PVI) to complex small interfering RNA (siRNA) silencing vascular endothelial growth factor (VEGF) and the in vitro efficiency of the formed complexes in A549 lung cancer cells. The polyplex formed was found to exhibit 66% complexation...

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Detalles Bibliográficos
Autores principales:	Kandasamy, Gayathri, Danilovtseva, Elena N, Annenkov, Vadim V, Krishnan, Uma Maheswari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2020
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061483/ https://www.ncbi.nlm.nih.gov/pubmed/32190532 http://dx.doi.org/10.3762/bjnano.11.26

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