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Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management
The presence of mammary nodules during childhood and adolescence is somewhat unusual, generally consisting of benign lesions. Despite the range of possible diagnoses, they are generally similar in clinical terms. In the rare cases where these lesions constitute a case of gigantomastia, the different...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061678/ https://www.ncbi.nlm.nih.gov/pubmed/32158862 http://dx.doi.org/10.1016/j.jpra.2018.08.003 |
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author | Morone, Isadora de Andrade, Guilherme Pansardi Cardoso, Paola Soares de Oliveira, Afrânio Coelho Clímaco, Flávia Medeiros, João Franco, Diogo |
author_facet | Morone, Isadora de Andrade, Guilherme Pansardi Cardoso, Paola Soares de Oliveira, Afrânio Coelho Clímaco, Flávia Medeiros, João Franco, Diogo |
author_sort | Morone, Isadora |
collection | PubMed |
description | The presence of mammary nodules during childhood and adolescence is somewhat unusual, generally consisting of benign lesions. Despite the range of possible diagnoses, they are generally similar in clinical terms. In the rare cases where these lesions constitute a case of gigantomastia, the differential diagnosis must be between juvenile fibroadenomatosis, phyllodes tumours and other even less common diseases of the mammary gland, such as Pseudoangiomatous Stromal Hyperplasia (PASH). This is caused by the exacerbated proliferation of mature fibroblasts and myofibroblasts, with the trigger factor still unknown. This study reports on a rare case of bilateral PASH in a young patient, describing its diagnosis and the surgical technique used. |
format | Online Article Text |
id | pubmed-7061678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-70616782020-03-10 Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management Morone, Isadora de Andrade, Guilherme Pansardi Cardoso, Paola Soares de Oliveira, Afrânio Coelho Clímaco, Flávia Medeiros, João Franco, Diogo JPRAS Open Case Reports and Short Communication The presence of mammary nodules during childhood and adolescence is somewhat unusual, generally consisting of benign lesions. Despite the range of possible diagnoses, they are generally similar in clinical terms. In the rare cases where these lesions constitute a case of gigantomastia, the differential diagnosis must be between juvenile fibroadenomatosis, phyllodes tumours and other even less common diseases of the mammary gland, such as Pseudoangiomatous Stromal Hyperplasia (PASH). This is caused by the exacerbated proliferation of mature fibroblasts and myofibroblasts, with the trigger factor still unknown. This study reports on a rare case of bilateral PASH in a young patient, describing its diagnosis and the surgical technique used. Elsevier 2018-09-19 /pmc/articles/PMC7061678/ /pubmed/32158862 http://dx.doi.org/10.1016/j.jpra.2018.08.003 Text en © 2018 Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Reports and Short Communication Morone, Isadora de Andrade, Guilherme Pansardi Cardoso, Paola Soares de Oliveira, Afrânio Coelho Clímaco, Flávia Medeiros, João Franco, Diogo Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
title | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
title_full | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
title_fullStr | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
title_full_unstemmed | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
title_short | Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management |
title_sort | bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: a challenge in reconstruction and management |
topic | Case Reports and Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061678/ https://www.ncbi.nlm.nih.gov/pubmed/32158862 http://dx.doi.org/10.1016/j.jpra.2018.08.003 |
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