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Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics
Nuclear factor κB (NF-κB) RelA is the potent transcriptional activator of inflammatory response genes. We stringently defined a list of direct RelA target genes by integrating physical (chromatin immunoprecipitation sequencing [ChIP-seq]) and functional (RNA sequencing [RNA-seq] in knockouts) datase...
Autores principales: | Ngo, Kim A., Kishimoto, Kensei, Davis-Turak, Jeremy, Pimplaskar, Aditya, Cheng, Zhang, Spreafico, Roberto, Chen, Emily Y., Tam, Amy, Ghosh, Gourisankar, Mitchell, Simon, Hoffmann, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061728/ https://www.ncbi.nlm.nih.gov/pubmed/32101750 http://dx.doi.org/10.1016/j.celrep.2020.01.108 |
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