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Pyruvate Kinase M2 and Cancer: The Role of PKM2 in Promoting Tumorigenesis

Pyruvate kinase plays a pivotal role in regulating cell metabolism. The final and rate-limiting step of glycolysis is the conversion of Phosphoenolpyruvate (PEP) to Pyruvate, which is catalyzed by Pyruvate Kinase. There are four isomeric, tissue-specific forms of Pyruvate Kinase found in mammals: PK...

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Detalles Bibliográficos
Autores principales:	Zahra, Kulsoom, Dey, Tulika, Ashish, Mishra, Surendra Pratap, Pandey, Uma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061896/ https://www.ncbi.nlm.nih.gov/pubmed/32195169 http://dx.doi.org/10.3389/fonc.2020.00159

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