Cargando…
Transcriptome visualization and data availability at the Saccharomyces Genome Database
The Saccharomyces Genome Database (SGD; www.yeastgenome.org) maintains the official annotation of all genes in the Saccharomyces cerevisiae reference genome and aims to elucidate the function of these genes and their products by integrating manually curated experimental data. Technological advances...
Autores principales: | , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061941/ https://www.ncbi.nlm.nih.gov/pubmed/31612944 http://dx.doi.org/10.1093/nar/gkz892 |
_version_ | 1783504466818891776 |
---|---|
author | Ng, Patrick C Wong, Edith D MacPherson, Kevin A Aleksander, Suzi Argasinska, Joanna Dunn, Barbara Nash, Robert S Skrzypek, Marek S Gondwe, Felix Jha, Sagar Karra, Kalpana Weng, Shuai Miyasato, Stuart Simison, Matt Engel, Stacia R Cherry, J Michael |
author_facet | Ng, Patrick C Wong, Edith D MacPherson, Kevin A Aleksander, Suzi Argasinska, Joanna Dunn, Barbara Nash, Robert S Skrzypek, Marek S Gondwe, Felix Jha, Sagar Karra, Kalpana Weng, Shuai Miyasato, Stuart Simison, Matt Engel, Stacia R Cherry, J Michael |
author_sort | Ng, Patrick C |
collection | PubMed |
description | The Saccharomyces Genome Database (SGD; www.yeastgenome.org) maintains the official annotation of all genes in the Saccharomyces cerevisiae reference genome and aims to elucidate the function of these genes and their products by integrating manually curated experimental data. Technological advances have allowed researchers to profile RNA expression and identify transcripts at high resolution. These data can be configured in web-based genome browser applications for display to the general public. Accordingly, SGD has incorporated published transcript isoform data in our instance of JBrowse, a genome visualization platform. This resource will help clarify S. cerevisiae biological processes by furthering studies of transcriptional regulation, untranslated regions, genome engineering, and expression quantification in S. cerevisiae. |
format | Online Article Text |
id | pubmed-7061941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-70619412020-03-13 Transcriptome visualization and data availability at the Saccharomyces Genome Database Ng, Patrick C Wong, Edith D MacPherson, Kevin A Aleksander, Suzi Argasinska, Joanna Dunn, Barbara Nash, Robert S Skrzypek, Marek S Gondwe, Felix Jha, Sagar Karra, Kalpana Weng, Shuai Miyasato, Stuart Simison, Matt Engel, Stacia R Cherry, J Michael Nucleic Acids Res Database Issue The Saccharomyces Genome Database (SGD; www.yeastgenome.org) maintains the official annotation of all genes in the Saccharomyces cerevisiae reference genome and aims to elucidate the function of these genes and their products by integrating manually curated experimental data. Technological advances have allowed researchers to profile RNA expression and identify transcripts at high resolution. These data can be configured in web-based genome browser applications for display to the general public. Accordingly, SGD has incorporated published transcript isoform data in our instance of JBrowse, a genome visualization platform. This resource will help clarify S. cerevisiae biological processes by furthering studies of transcriptional regulation, untranslated regions, genome engineering, and expression quantification in S. cerevisiae. Oxford University Press 2020-01-08 2019-10-15 /pmc/articles/PMC7061941/ /pubmed/31612944 http://dx.doi.org/10.1093/nar/gkz892 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Database Issue Ng, Patrick C Wong, Edith D MacPherson, Kevin A Aleksander, Suzi Argasinska, Joanna Dunn, Barbara Nash, Robert S Skrzypek, Marek S Gondwe, Felix Jha, Sagar Karra, Kalpana Weng, Shuai Miyasato, Stuart Simison, Matt Engel, Stacia R Cherry, J Michael Transcriptome visualization and data availability at the Saccharomyces Genome Database |
title | Transcriptome visualization and data availability at the Saccharomyces Genome Database |
title_full | Transcriptome visualization and data availability at the Saccharomyces Genome Database |
title_fullStr | Transcriptome visualization and data availability at the Saccharomyces Genome Database |
title_full_unstemmed | Transcriptome visualization and data availability at the Saccharomyces Genome Database |
title_short | Transcriptome visualization and data availability at the Saccharomyces Genome Database |
title_sort | transcriptome visualization and data availability at the saccharomyces genome database |
topic | Database Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061941/ https://www.ncbi.nlm.nih.gov/pubmed/31612944 http://dx.doi.org/10.1093/nar/gkz892 |
work_keys_str_mv | AT ngpatrickc transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT wongedithd transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT macphersonkevina transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT aleksandersuzi transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT argasinskajoanna transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT dunnbarbara transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT nashroberts transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT skrzypekmareks transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT gondwefelix transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT jhasagar transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT karrakalpana transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT wengshuai transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT miyasatostuart transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT simisonmatt transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT engelstaciar transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase AT cherryjmichael transcriptomevisualizationanddataavailabilityatthesaccharomycesgenomedatabase |