Human transposon insertion profiling by sequencing (TIPseq) to map LINE-1 insertions in single cells

Long interspersed element-1 (LINE-1, L1) sequences, which comprise about 17% of human genome, are the product of one of the most active types of mobile DNAs in modern humans. LINE-1 insertion alleles can cause inherited and de novo genetic diseases, and LINE-1-encoded proteins are highly expressed i...

Descripción completa

Detalles Bibliográficos
Autores principales: McKerrow, Wilson, Tang, Zuojian, Steranka, Jared P., Payer, Lindsay M., Boeke, Jef D., Keefe, David, Fenyö, David, Burns, Kathleen H., Liu, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061987/
https://www.ncbi.nlm.nih.gov/pubmed/32075555
http://dx.doi.org/10.1098/rstb.2019.0335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061987/
https://www.ncbi.nlm.nih.gov/pubmed/32075555
http://dx.doi.org/10.1098/rstb.2019.0335

Ejemplares similares