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Cell-free IgG-aggregates in plasma of patients with chronic lymphocytic leukemia cause chronic activation of the classical complement pathway

Therapy regimens for Chronic lymphocytic leukemia (CLL) commonly include chemotherapy and immunotherapy, which act through complement-mediated-cytotoxicity (CDC) and other mechanisms. CDC depends on several factors, including the availability and activity of the complement classical pathway (CP). Re...

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Detalles Bibliográficos
Autores principales:	Michelis, Regina, Tadmor, Tamar, Aviv, Ariel, Stemer, Galia, Majdob, Rawan, Shvidel, Lev, Shehadeh, Mona, Barhoum, Masad, Braester, Andrei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062264/ https://www.ncbi.nlm.nih.gov/pubmed/32150580 http://dx.doi.org/10.1371/journal.pone.0230033

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