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Study on the Formation of Antihypertensive Twin Drugs by Caffeic Acid and Ferulic Acid with Telmisartan

PURPOSE: This study aimed to synthesize twin drugs from cinnamic acid compounds, caffeic acid (CFA) and ferulic acid (FLA), which can antagonize endothelin-1 (ET-1) with telmisartan through ester bonds. Moreover, the antihypertensive effect of telmisartan and its influence on blood pressure variabil...

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Detalles Bibliográficos
Autores principales: Li, Pengshou, Peng, Yingying, Ma, Qixiang, Li, Ziyong, Zhang, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062412/
https://www.ncbi.nlm.nih.gov/pubmed/32184567
http://dx.doi.org/10.2147/DDDT.S225705

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