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Study on the Formation of Antihypertensive Twin Drugs by Caffeic Acid and Ferulic Acid with Telmisartan
PURPOSE: This study aimed to synthesize twin drugs from cinnamic acid compounds, caffeic acid (CFA) and ferulic acid (FLA), which can antagonize endothelin-1 (ET-1) with telmisartan through ester bonds. Moreover, the antihypertensive effect of telmisartan and its influence on blood pressure variabil...
Autores principales: | Li, Pengshou, Peng, Yingying, Ma, Qixiang, Li, Ziyong, Zhang, Xiaohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062412/ https://www.ncbi.nlm.nih.gov/pubmed/32184567 http://dx.doi.org/10.2147/DDDT.S225705 |
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