Cargando…
Microglial depletion disrupts normal functional development of adult-born neurons in the olfactory bulb
Microglia play key roles in regulating synapse development and refinement in the developing brain, but it is unknown whether they are similarly involved during adult neurogenesis. By transiently depleting microglia from the healthy adult mouse brain, we show that microglia are necessary for the norm...
Autores principales: | Wallace, Jenelle, Lord, Julia, Dissing-Olesen, Lasse, Stevens, Beth, Murthy, Venkatesh N |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062469/ https://www.ncbi.nlm.nih.gov/pubmed/32150529 http://dx.doi.org/10.7554/eLife.50531 |
Ejemplares similares
-
Neuronal integration in the adult mouse olfactory bulb is a non-selective addition process
por: Platel, Jean-Claude, et al.
Publicado: (2019) -
Olfactory cortical neurons read out a relative time code in the olfactory bulb
por: Haddad, Rafi, et al.
Publicado: (2013) -
Postnatal Development of Dendrodendritic Inhibition in the Mammalian Olfactory Bulb
por: Dietz, Shelby B., et al.
Publicado: (2011) -
Microglial response patterns following damage to the zebrafish olfactory bulb
por: Var, Susanna R., et al.
Publicado: (2019) -
Olfactory Sensory Activity Modulates Microglial-Neuronal Interactions during Dopaminergic Cell Loss in the Olfactory Bulb
por: Grier, Bryce D., et al.
Publicado: (2016)