Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth

Cancer cells often proliferate under hypoxia and reprogram their metabolism. However, how to find targets to effectively block the hypoxia-associated metabolic pathways remains unclear. Here, we developed a tool to conveniently calculate electrons dissipated in metabolic transformations. Based on th...

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Detalles Bibliográficos
Autores principales: Liu, Miao, Wang, Yuanyuan, Yang, Chuanzhen, Ruan, Yuxia, Bai, Changsen, Chu, Qiaoyun, Cui, Yanfen, Chen, Ceshi, Ying, Guoguang, Li, Binghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062513/
https://www.ncbi.nlm.nih.gov/pubmed/31961917
http://dx.doi.org/10.1084/jem.20191226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062513/
https://www.ncbi.nlm.nih.gov/pubmed/31961917
http://dx.doi.org/10.1084/jem.20191226

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