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The transcription factor NFAT5 limits infection-induced type I interferon responses

Type I interferon (IFN-I) provides effective antiviral immunity but can exacerbate harmful inflammatory reactions and cause hematopoietic stem cell (HSC) exhaustion; therefore, IFN-I expression must be tightly controlled. While signaling mechanisms that limit IFN-I induction and function have been e...

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Detalles Bibliográficos
Autores principales: Huerga Encabo, Hector, Traveset, Laia, Argilaguet, Jordi, Angulo, Ana, Nistal-Villán, Estanislao, Jaiswal, Rahul, Escalante, Carlos R., Gekas, Christos, Meyerhans, Andreas, Aramburu, Jose, López-Rodríguez, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062515/
https://www.ncbi.nlm.nih.gov/pubmed/31816635
http://dx.doi.org/10.1084/jem.20190449

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