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Dynamics of human monocytes and airway macrophages during healthy aging and after transplant
The ontogeny of airway macrophages (AMs) in human lung and their contribution to disease are poorly mapped out. In mice, aging is associated with an increasing proportion of peripherally, as opposed to perinatally derived AMs. We sought to understand AM ontogeny in human lung during healthy aging an...
Autores principales: | Byrne, Adam J., Powell, Joseph E., O’Sullivan, Brendan J., Ogger, Patricia P., Hoffland, Ashley, Cook, James, Bonner, Katie L., Hewitt, Richard J., Wolf, Simone, Ghai, Poonam, Walker, Simone A., Lukowski, Samuel W., Molyneaux, Philip L., Saglani, Sejal, Chambers, Daniel C., Maher, Toby M., Lloyd, Clare M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062517/ https://www.ncbi.nlm.nih.gov/pubmed/31917836 http://dx.doi.org/10.1084/jem.20191236 |
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