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The human fetal thymus generates invariant effector γδ T cells

In the mouse thymus, invariant γδ T cells are generated at well-defined times during development and acquire effector functions before exiting the thymus. However, whether such thymic programming and age-dependent generation of invariant γδ T cells occur in humans is not known. Here we found that, u...

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Detalles Bibliográficos
Autores principales: Tieppo, Paola, Papadopoulou, Maria, Gatti, Deborah, McGovern, Naomi, Chan, Jerry K.Y., Gosselin, Françoise, Goetgeluk, Glenn, Weening, Karin, Ma, Ling, Dauby, Nicolas, Cogan, Alexandra, Donner, Catherine, Ginhoux, Florent, Vandekerckhove, Bart, Vermijlen, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062527/
https://www.ncbi.nlm.nih.gov/pubmed/31816633
http://dx.doi.org/10.1084/jem.20190580