Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2

Antibiotic-induced dysbiosis is a key predisposing factor for Clostridium difficile infections (CDIs), which cause intestinal disease ranging from mild diarrhea to pseudomembranous colitis. Here, we examined the impact of a microbiota-derived metabolite, short-chain fatty acid acetate, on an acute m...

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Detalles Bibliográficos
Autores principales: Fachi, José Luís, Sécca, Cristiane, Rodrigues, Patrícia Brito, de Mato, Felipe Cézar Pinheiro, Di Luccia, Blanda, Felipe, Jaqueline de Souza, Pral, Laís Passariello, Rungue, Marcella, Rocha, Victor de Melo, Sato, Fabio Takeo, Sampaio, Ulliana, Clerici, Maria Teresa Pedrosa Silva, Rodrigues, Hosana Gomes, Câmara, Niels Olsen Saraiva, Consonni, Sílvio Roberto, Vieira, Angélica Thomaz, Oliveira, Sergio Costa, Mackay, Charles Reay, Layden, Brian T., Bortoluci, Karina Ramalho, Colonna, Marco, Vinolo, Marco Aurélio Ramirez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062529/
https://www.ncbi.nlm.nih.gov/pubmed/31876919
http://dx.doi.org/10.1084/jem.20190489

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