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Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion models
In healthy individuals, immune control of persistent human cytomegalovirus (HCMV) infection is effectively mediated by virus-specific CD4(+) and CD8(+) T cells. However, identifying the repertoire of T cell specificities for HCMV is hampered by the immense protein coding capacity of this betaherpesv...
Autores principales: | Lübke, Maren, Spalt, Stefanie, Kowalewski, Daniel J., Zimmermann, Cosima, Bauersfeld, Liane, Nelde, Annika, Bichmann, Leon, Marcu, Ana, Peper, Janet Kerstin, Kohlbacher, Oliver, Walz, Juliane S., Le-Trilling, Vu Thuy Khanh, Hengel, Hartmut, Rammensee, Hans-Georg, Stevanović, Stefan, Halenius, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062530/ https://www.ncbi.nlm.nih.gov/pubmed/31869419 http://dx.doi.org/10.1084/jem.20191164 |
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