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Human IgA binds a diverse array of commensal bacteria

In humans, several grams of IgA are secreted every day in the intestinal lumen. While only one IgA isotype exists in mice, humans secrete IgA1 and IgA2, whose respective relations with the microbiota remain elusive. We compared the binding patterns of both polyclonal IgA subclasses to commensals and...

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Detalles Bibliográficos
Autores principales: Sterlin, Delphine, Fadlallah, Jehane, Adams, Olivia, Fieschi, Claire, Parizot, Christophe, Dorgham, Karim, Rajkumar, Asok, Autaa, Gaëlle, El-Kafsi, Hela, Charuel, Jean-Luc, Juste, Catherine, Jönsson, Friederike, Candela, Thomas, Wardemann, Hedda, Aubry, Alexandra, Capito, Carmen, Brisson, Hélène, Tresallet, Christophe, Cummings, Richard D., Larsen, Martin, Yssel, Hans, von Gunten, Stephan, Gorochov, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062531/
https://www.ncbi.nlm.nih.gov/pubmed/31891367
http://dx.doi.org/10.1084/jem.20181635