Inhibition of Histone H3K27 Acetylation Orchestrates Interleukin-9-Mediated and Plays an Anti-Inflammatory Role in Cisplatin-Induced Acute Kidney Injury

Nephrotoxicity is a major side effect of cisplatin (CP)- and platinum-related chemotherapy, and inflammation contributes to disease pathogenesis. Interleukin-9 (IL-9) is a pleiotropic cytokine associated with inflammation. Here, we investigated the key role of IL-9 as a regulator of protective mecha...

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Detalles Bibliográficos
Autores principales: Jiang, Wenjuan, Yuan, Xinrong, Zhu, Hong, He, Changsheng, Ge, Caiqiong, Tang, Qing, Xu, Chuanting, Hu, Bingfeng, Huang, Cheng, Ma, Taotao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062682/
https://www.ncbi.nlm.nih.gov/pubmed/32194547
http://dx.doi.org/10.3389/fimmu.2020.00231

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