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GlnR Dominates Rifamycin Biosynthesis by Activating the rif Cluster Genes Transcription Both Directly and Indirectly in Amycolatopsis mediterranei

Because of the remarkable efficacy in treating mycobacterial infections, rifamycin and its derivatives are still first-line antimycobacterial drugs. It has been intensely studied to increase rifamycin yield from Amycolatopsis mediterranei, and nitrate is found to provide a stable and remarkable stim...

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Detalles Bibliográficos
Autores principales:	Liu, Xinqiang, Liu, Yuanyuan, Lei, Chao, Zhao, Guoping, Wang, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062684/ https://www.ncbi.nlm.nih.gov/pubmed/32194530 http://dx.doi.org/10.3389/fmicb.2020.00319

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