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Full-length human GLP-1 receptor structure without orthosteric ligands

Glucagon-like peptide-1 receptor (GLP-1R) is a class B G protein-coupled receptor that plays an important role in glucose homeostasis and treatment of type 2 diabetes. Structures of full-length class B receptors were determined in complex with their orthosteric agonist peptides, however, little is k...

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Detalles Bibliográficos
Autores principales:	Wu, Fan, Yang, Linlin, Hang, Kaini, Laursen, Mette, Wu, Lijie, Han, Gye Won, Ren, Qiansheng, Roed, Nikolaj Kulahin, Lin, Guangyao, Hanson, Michael A., Jiang, Hualiang, Wang, Ming-Wei, Reedtz-Runge, Steffen, Song, Gaojie, Stevens, Raymond C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062719/ https://www.ncbi.nlm.nih.gov/pubmed/32152292 http://dx.doi.org/10.1038/s41467-020-14934-5

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