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NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium

This study sought to evaluate the association of 28 single nucleotide polymorphisms (SNPs) within NFKB and inflammasome pathway genes with the risk of rheumatoid arthritis (RA) and response to TNF inhibitors (TNFi). We conducted a case-control study in a European population of 1194 RA patients and 1...

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Detalles Bibliográficos
Autores principales: Manuel Sánchez-Maldonado, Jose, Martínez-Bueno, Manuel, Canhão, Helena, ter Horst, Rob, Muñoz-Peña, Sonia, Moñiz-Díez, Ana, Rodríguez-Ramos, Ana, Escudero, Alejandro, Sorensen, Signe B., Hetland, Merete L., Ferrer, Miguel A., Glintborg, Bente, Filipescu, Ileana, Pérez-Pampin, Eva, Conesa-Zamora, Pablo, García, Antonio, den Broeder, Alfons, De Vita, Salvatore, Hove Jacobsen, Svend Erik, Collantes, Eduardo, Quartuccio, Luca, Netea, Mihai G., Li, Yang, Fonseca, João E., Jurado, Manuel, López-Nevot, Miguel Ángel, Coenen, Marieke J. H., Andersen, Vibeke, Cáliz, Rafael, Sainz, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062729/
https://www.ncbi.nlm.nih.gov/pubmed/32152480
http://dx.doi.org/10.1038/s41598-020-61331-5