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Human HMGN1 and HMGN2 are not required for transcription-coupled DNA repair

Transcription-coupled repair (TCR) removes DNA lesions from the transcribed strand of active genes. Stalling of RNA polymerase II (RNAPII) at DNA lesions initiates TCR through the recruitment of the CSB and CSA proteins. The full repertoire of proteins required for human TCR – particularly in a chro...

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Detalles Bibliográficos
Autores principales: Apelt, Katja, Zoutendijk, Iris, Gout, Dennis Y., Wondergem, Annelotte P., van den Heuvel, Diana, Luijsterburg, Martijn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062826/
https://www.ncbi.nlm.nih.gov/pubmed/32152397
http://dx.doi.org/10.1038/s41598-020-61243-4