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DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria

The DJ-1 gene, a causative gene for familial Parkinson’s disease (PD), has been reported to have various functions, including transcriptional regulation, antioxidant response, and chaperone and protease functions; however, the molecular mechanism associated with the pathogenesis of PD remains elusiv...

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Detalles Bibliográficos
Autores principales: Ozawa, Kentaro, Tsumoto, Hiroki, Miura, Yuri, Yamaguchi, Junji, Iguchi-Ariga, Sanae M. M., Sakuma, Tetsushi, Yamamoto, Takashi, Uchiyama, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062835/
https://www.ncbi.nlm.nih.gov/pubmed/32152416
http://dx.doi.org/10.1038/s41598-020-61287-6