Cargando…
Shared genetic etiology underlying Alzheimer’s disease and major depressive disorder
Patients with late-onset Alzheimer’s disease (LOAD) frequently manifest comorbid neuropsychiatric symptoms with depression and anxiety being most frequent, and individuals with major depressive disorder (MDD) have an increased prevalence of LOAD. This suggests shared etiologies and intersecting path...
Autores principales: | Lutz, Michael W., Sprague, Daniel, Barrera, Julio, Chiba-Falek, Ornit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062839/ https://www.ncbi.nlm.nih.gov/pubmed/32152295 http://dx.doi.org/10.1038/s41398-020-0769-y |
Ejemplares similares
-
Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer’s Disease Based on Major Depressive Disorder Risk Variants
por: Upadhya, Suraj, et al.
Publicado: (2022) -
Probing the role of PPARγ in the regulation of late-onset Alzheimer’s disease-associated genes
por: Barrera, Julio, et al.
Publicado: (2018) -
The Role of Upregulated APOE in Alzheimer’s Disease Etiology
por: Gottschalk, William K, et al.
Publicado: (2016) -
Bioinformatics pipeline to guide late‐onset Alzheimer's disease (LOAD) post‐GWAS studies: Prioritizing transcription regulatory variants within LOAD‐associated regions
por: Lutz, Michael W., et al.
Publicado: (2022) -
Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders
por: Gamache, Julia, et al.
Publicado: (2020)