The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage

Prolonged cell survival occurs through the expression of specific protein isoforms generated by alternate splicing of mRNA precursors in cancer cells. How alternate splicing regulates tumor development and resistance to targeted therapies in cancer remain poorly understood. Here we show that RNF113A...

Descripción completa

Detalles Bibliográficos
Autores principales: Shostak, Kateryna, Jiang, Zheshen, Charloteaux, Benoit, Mayer, Alice, Habraken, Yvette, Tharun, Lars, Klein, Sebastian, Xu, Xinyi, Duong, Hong Quan, Vislovukh, Andrii, Close, Pierre, Florin, Alexandra, Rambow, Florian, Marine, Jean-Christophe, Büttner, Reinhard, Chariot, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062854/
https://www.ncbi.nlm.nih.gov/pubmed/32152280
http://dx.doi.org/10.1038/s41467-020-15003-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062854/
https://www.ncbi.nlm.nih.gov/pubmed/32152280
http://dx.doi.org/10.1038/s41467-020-15003-7

Ejemplares similares