New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells

Serrated adenocarcinoma (SAC) is more invasive, has worse outcomes than conventional colorectal carcinoma (CRC), and is characterized by frequent resistance to anti-epidermal growth factor receptor (EGFR) and overexpression of fascin1, a key protein in actin bundling that plays a causative role in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Alburquerque-González, Begoña, Bernabé-García, Manuel, Montoro-García, Silvia, Bernabé-García, Ángel, Rodrigues, Priscila Campioni, Ruiz Sanz, Javier, López-Calderón, Fernando F., Luque, Irene, Nicolas, Francisco José, Cayuela, María Luisa, Salo, Tuula, Pérez-Sánchez, Horacio, Conesa-Zamora, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062870/
https://www.ncbi.nlm.nih.gov/pubmed/32080340
http://dx.doi.org/10.1038/s12276-020-0389-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062870/
https://www.ncbi.nlm.nih.gov/pubmed/32080340
http://dx.doi.org/10.1038/s12276-020-0389-x

Ejemplares similares